Michigan has quietly become one of the most important cannabis markets in the United States. In 2023 alone, the state logged roughly $3 billion in combined medical and adult-use sales, ranking it among the top cannabis markets in the country.

Behind those numbers is a mix of homegrown operators and multi-state companies, all fighting for share in a crowded field of 800+ licensed businesses. Below is a look at three standout cannabis companies in Michigan—from a dominant single-state local player to Michigan-based MSOs that now reach far beyond state borders.

1. Lume Cannabis Co. – Michigan’s Homegrown Giant (Local Single-State Operator)

If you ask industry watchers who dominates the retail landscape in Michigan, Lume Cannabis Co. is almost always part of the conversation.

• Lume markets itself as “Michigan’s largest cannabis company” and “Michigan’s best dispensary,” with a large footprint of branded stores across the state. SITE: Lume
• By late 2024, Lume operated 38 dispensary locations across Michigan, backed by both indoor and outdoor cultivation facilities. READ MORE: Cannabis Business Times
• A 2024 feature on Mt. Pleasant’s cannabis scene described Lume as the largest single-state operator with 38 locations, reinforcing its position as a uniquely Michigan-focused heavyweight. READ MORE: Epicenter Mt Pleasant

Unlike many big retail chains, Lume has chosen to stay exclusively in Michigan, building a vertically integrated model: large-scale cultivation, in-house brands, and tightly controlled retail. Coverage from Cannabis Business Times and local media notes that Lume has grown from a small startup to nearly $200 million in annual revenue in just a few years, using scale to offer aggressive pricing and deep menus.

Lume also invests heavily in customer experience. A 2025 piece on its Big Rapids location highlighted a new “open floor” design with a horseshoe-shaped display counter, a “bud bar” with over 100 smell-pods, and a more self-guided shopping experience—signaling how serious the company is about retail innovation in Michigan.

Why Lume matters:

• It’s the quintessential Michigan local champion, employing more than a thousand people and proving a single-state strategy can still scale.
• Its mix of indoor, outdoor, and manufactured products means Lume shapes wholesale prices, brand visibility, and consumer expectations statewide.

2. JARS Cannabis – Michigan-Founded Retailer With #1 Market Share (Regional MSO)

While Lume dominates as a vertically integrated single-state operator, JARS Cannabis has rapidly become a retail powerhouse with deep Michigan roots and multi-state reach.

• JARS began as a single shop in East Detroit and has grown into a chain with 47 locations across Arizona, Colorado, and Michigan, positioning itself as a value-driven, high-volume retailer. SITE: JARS Cannabis
• A 2025 LinkedIn market update from a JARS executive called the brand “#1 in Michigan cannabis market share,” citing 30+ Michigan locations, $250M+ in annual revenue, and over 1,100 employees.)
• A 2025 marketing analysis of Michigan’s dispensary landscape notes that JARS “maintains nearly 20 locations” in the state (some counts vary by timing) and emphasizes its “hip, community-focused” atmosphere and competitive pricing. MORE ABOUT: The Cannabis Marketing Agency

JARS positions itself as accessible and affordable, leaning into bold branding, deals, and a broad menu of third-party brands. Unlike Lume, which pushes its own products heavily, JARS operates more like a multi-brand retail platform, giving shelf space to a wide range of Michigan cultivators and manufacturers.

Because it operates in multiple states, JARS functions as a regional MSO, but it’s still Michigan-founded and Michigan-led, which gives it a different character than larger, publicly traded operators headquartered elsewhere.

Why JARS matters:

• It shows how a Detroit-born retailer can grow into a multi-state chain while still leading market share back home.
• Its scale and pricing pressure help define the “everyday dispensary” experience for many Michigan consumers, especially in metro areas.

3. C3 Industries / High Profile – Michigan-Headquartered MSO With National Reach

For a true Michigan-based MSO with a national footprint, C3 Industries stands out.

• C3 Industries is a vertically integrated, multi-state cannabis company headquartered in Ann Arbor, Michigan, operating cultivation, manufacturing, and retail in several states. SITE: C3 Industries
• The company runs a network of High Profile Cannabis Shop dispensaries, with locations in Michigan, Missouri, Massachusetts, Illinois, New Jersey, and Connecticut.
• Industry profiles emphasize that C3 was built organically out of competitive markets like Michigan and Oregon, rather than via large mergers, and that it focuses on strong in-house brands such as Cloud Cover Cannabis and Galactic Cannabis.

Recent news shows how far the company has scaled from its Michigan base:

• In 2024–25, C3 continued opening new High Profile locations in New Jersey and Connecticut, with local press repeatedly describing it as a “Michigan-based multi-state cannabis operator.” READ MORE: NJB Magazine

Back inside Michigan, C3 has become a serious competitor in both wholesale and retail, with High Profile stores often positioned as destination dispensaries in college towns and highway corridors. Its Michigan origin shapes company culture, but its multi-state footprint forces it to compete at a national level on branding, consistency, and compliance.

Why C3 matters:

• It represents the Michigan-grown MSO archetype: rooted in the state, but not limited by it.
• Its High Profile stores help bring Michigan genetics and brands to other legal markets, exporting some of the state’s cannabis culture nationwide.

Why These Three Companies Stand Out

Michigan’s cannabis map is crowded—other notable players include chains like House of Dank, regional wholesalers moving into retail, and national MSOs that have dipped in and out of the state. But these three companies illustrate the key dynamics shaping Michigan’s market:

1. Lume Cannabis Co. – A single-state local powerhouse, proving that scale and strong branding don’t require multi-state expansion.
2. JARS Cannabis – A Michigan-founded retailer that’s translated local success into regional MSO growth, while capturing top market share at home.
3. C3 Industries / High Profile – A Michigan-headquartered MSO using its Ann Arbor base and strong brand portfolio to compete across multiple states.

Together, they show how Michigan has evolved from an emerging market into a launchpad for serious national players, even as local operators continue to define what cannabis retail looks like from Detroit to the U.P.